Enzymuria-Early Predictors of Acute Kidney Injury in Animals

نویسندگان

چکیده

Enzymuria is recently being used as valuable tool for the diagnosis of acute kidney injury (AKI), and urinalysis in clinical cases. The origin enzymes from different parts has diagnostic importance. Enzymes origin, namely those brush border proximal tubuli were recognized their significance inanimals. Now a days, are more specifically tubular markers which determine location severity damage. These glutathione S-transferase (GST), N-acetyl-β-D-glucosaminidase (NAG), β-galactosidase (β-GAL), γ-glutamyltranspeptidase alkaline phosphatase early injury. Normally, originates serum (as glomerular filtrate), renal cells, urogenital tract (epithelial glandular secretion, semen). contribution negligible most urinary because they relatively larger (> 80 kDa), due to marker do not sieve through membrane appear urine. Urinary have also been presence Some bacterial or viral infections can damage tubules, result leakage some epithelium. Various nephrotoxic drugs therapeutics, along with contrast media may lead be released Especially, NAG- lysosomal enzyme epithelium into urine response could increased identified infected animals.

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ژورنال

عنوان ژورنال: The Indian Journal of Veterinary Sciences and Biotechnology

سال: 2023

ISSN: ['2394-0247', '2395-1176']

DOI: https://doi.org/10.48165/ijvsbt.19.2.01